Spider-Man 2

From The Amazing Spider-cast:

The first commentary was so much fun, Chris and Jen decided to space them out over a few weeks rather than months, and the commentary on Spider-Man 2 has it all. Guests Juan Castro and Chris Gallo? Check. Dirty jokes? Check. Doc Ock man boobs? Check. So sit back, relax, pop in Spider-Man 2, and enjoy.

[female voice] I love everything about this Doc Oc. … Even the man-boobs? Especially the man-boobs. I love me some double-D guy-boobs. — Amazing Spider-Cast,
Spider-Man 2 @0:13:52

You know it’s on when the nerd drops the specs. And the nose flare. Was that a CGI nose flare? … They paid $200,000 for that effect. — Amazing Spider-Cast,
Spider-Man 2 @1:44:00